Parkinson’s disease (PD) is a widespread, age-related, fatal neurodegenerative disorder that impairs movement and is accompanied by dementia, affecting 3% of the global population over the age of 65.1 The most prominent neuropathological hallmarks of PD are the presence of intracellular inclusions containing misfolded α-synuclein (α-syn) aggregates, such as Lewy bodies (LB) and Lewy neuritis, and progressive dopaminergic neurodegeneration in the substantia nigra pars compacta (SNpc). Here, SNCA is linked to Parkinson disease.