The hypothesis that circulating levels of AMH could act as a surrogate biomarker of follicular fluid oxidative stress in PCOS, along with its importance in predicting disease severity and reproductive prognosis in women with PCOS undergoing IVF ttreatments, make the proposal to include AMH in the review of PCOS diagnostic and classification criteria quite pertinent and useful. The gene discussed is AMH; the disease is polycystic ovary syndrome.