The initial laboratory investigations revealed leukocytosis of 14,000 leukocytes/μl, elevated C-reactive protein of 144 mg/l (normal range <5 mg/l), creatinine of 133 umul/L (normal range 62-106 umul/L), and minimal alteration of hepatic transaminases (aspartate transaminase (AST): 49 U/L, alanine transaminase (ALT): 103 U/L). The gene discussed is GPT; the disease is Increased total leukocyte count.