SERPINE1 and congenital dyserythropoietic anemia: The accuracies to distinguish severe CDA FCCM patients were considered as “fair” when using ROBO4 (AUC = 0.780, sensitivity 0.917, specificity 0.680, cutoff point 10.58 pg/mL) and as “good” when using E1/PAI-1 as markers (AUC = 0.813, sensitivity 0.750, specificity 0.840, cutoff point 106706.00 pg/mL) (Fig. 4f–h).