Other T cell subsets, especially those expressing the chemokine receptor CCR4/CD194, including memory CD4+CD196-CD183-CD194+, CD8+CD196-CD183-CD194+, and CD8+CD196+CD183-CD194+ were significantly higher in T1D (both percentages and absolute numbers, Figure 1B and Supplementary Figure S3). This evidence concerns the gene CD4 and type 1 diabetes mellitus.