For T1D-group-B negative correlations were found with CD8+CD196-CD183-CD194+, CD8+CD196+CD183-CD194+ and CD4+CD196+CD183-CD194+, while CD8+CD196+CD183-CD194- correlated positively to IL-10 (Figure 4B). This evidence concerns the gene CCR4 and type 1 diabetes mellitus.