TP53 and atherosclerosis: These pathways, including apoptosis, p53 signaling pathway, cholesterol metabolism, TLR signaling pathway, NF-kappa B signaling pathway, lipid and atherosclerosis, NOD-like receptor signaling pathway, IL-17 signaling pathway, necroptosis, cellular senescence, and PI3K-Akt signaling pathway, are implicated in the pathological development of SCI.