The miR-142 is highly correlated with THBS4 overexpression in HCC tissue samples, by regulating THBS4 expression in HCC cells [36], PPP1R16A encoded the membrane-associated subunit of protein phosphatase 1 which is located on the plasma membrane as a CAR-binding protein [37]. This evidence concerns the gene PPP1R16A and hepatocellular carcinoma.