Results from the analysis with the non-cancer multi-tissue network and the colon cancer GWAS included the genes KMT2B, PTBP1 and GEN1 (p-values 2.0 × 10− 6, 3.0 × 10− 6 and 3.0 × 10− 6, respectively). This evidence concerns the gene GEN1 and colonic neoplasm.