Diarrhoea, nausea, vomiting, fatigue, ECG QT prolonged, aspartate aminotransferase (AST) increased, alanine aminotransferase (ALT) increased, amylase increase, blood creatinine increase/acute kidney injury, decreased appetite, and anaemia were the very common (≥ 10%) any grade trAEs. The gene discussed is GPT; the disease is acute kidney injury.