ITGB1, a demethylated target whose m6A RNA modification sites are generally located in the 3′-UTR of mRNA of FTO in GC, played a role in the growth of multiple tumors. The increased ITGB1 expression promoted migration and invasion abilities of GC cells via decreasing its mRNA m6A RNA modification level [46]. This evidence concerns the gene ITGB1 and gastric cancer.