With regard to clinical relevance, MEF3-related genes TRAF1 and TNFSF9, as well as direct cis-targets of DiPRO1 (Dataset EV1A,B) that transcriptionally respond to DiPRO1 KD in RMS and Ewing sarcoma cells in vitro (Dataset EV3), were analyzed in biopsies of recurrent tumors. Here, TNFSF9 is linked to Ewing sarcoma.