Studies have reported that TNFRSF9 suppresses tumor progression in breast cancer (Liu et al, 2022) and that TNFSF9 reverse signaling induces apoptosis in non-small cell lung cancer cells (Qian et al, 2015), suggesting a potential role in the antitumor activity of DiPRO1. The gene discussed is TNFRSF9; the disease is breast cancer.