CD4 and infectious otitis media: Significantly higher cell counts of CD4 positive and CD8 positive T cells were observed in the spleen (Fig. 3A), mesenteric lymph nodes (Fig. 3B), as well as colon tissues (Appendix Fig. S7) of the mice receiving LPS-primed neutrophils compared with the mice receiving PBS-primed neutrophils during AOM-DSS treatment.