A similar expression pattern was found in mouse tumour allografts, where low-grade differentiated tumours (KPCe and KPCZ, Zeb1low) expressed higher levels of SCD and FASN, and lower levels of FADS2, ELOVL5 and ACSL4, whereas cancer cells in high-grade undifferentiated tumours (KPCm and Zeb1high) showed a reverse expression pattern (Fig. 3c and Extended Data Fig. 4c). This evidence concerns the gene ACSL4 and cancer.