Of the 12 altered protein, 5 protein-disease causalities were supported by MR, i.e., LTA-celiac disease (PIVW = 1.29 × 10−3), IL18BP-Crohn’s disease (PIVW = 4.04 × 10−2), DDR1-Graves’ disease (PIVW = 3.37 × 10−3), CDSN-psoriasis (PIVW = 4.02 × 10−7), and BTN3A2-SD (PIVW = 3.93×10−5). Here, BTN3A2 is linked to celiac disease.