Aligned with a prior study34, we found that VEGFA was associated with multiple sclerosis (MS, 1.10, P = 6.04 × 10−7), but our study also unraveled two novel genes, LRRC74A (1.08, P = 4.20 × 10−7) and ZNF266 (1.08, P = 1.10 × 0−7). This evidence concerns the gene LRRC74A and multiple sclerosis.