MEPCE and neurodevelopmental disorder: Patients with MePCE mutations exhibit a neurodevelopmental disorder phenotype similar to that of patients with loss-of-function mutations in LARP7. Bin3/MePCE 1 (Bmc1) is the putative fission yeast orthologue of MePCE and cooperates with Pof8 to recognize correctly folded TER130,31.