Our analysis revealed potential binding to several other kinases believed to be involved with disease pathogenesis: Abl, SYK, and SRC have also been associated with neurodegenerative disease pathology, including microglial activation and tau phosphorylation, and have been investigated as therapeutic targets (Dhawan & Combs, 2012; Hebron et al, 2013b; Mahul-Mellier et al, 2014; Nygaard et al, 2014). This evidence concerns the gene MAPT and neurodegenerative disease.