PIP5K1A and cancer: PIKFYVE and PIP5K1A are enzymes targeted as therapies for cancer, as their inhibition has been shown to induce autophagy (O’Connell & Vassilev, 2021; Rong et al, 2012), further suggesting our compounds as inducers of autophagy, as both compounds led to an increase in beclin-1 levels (Sarkar, 2013).