To determine binding specificity, sections of subcutaneously grown U87-CXCR4 + tumours and sections of mouse brain with an inoculated U87-CXCR4 + tumour, were incubated with 5 nM [177Lu]Lu-POL3026 and treated with vehicle or 100 μM AMD11070 (Fig. 8). The gene discussed is CXCR4; the disease is neoplasm.