We searched for the presence of auto-Abs against nine cytokines (IFN-α, IFN-β, IFN-ω, IFN-γ, IL-12p40, IL-17 A, IL-23, IL-6 and GM-CSF) in the serum samples of the 30 patients with cryptococcosis. The gene discussed is IFNB1; the disease is cryptococcosis.