The blockade of CXCL8 using the neutralizing antibody inhibited M2 polarization of macrophages induced by gastric cancer-derived mesenchymal stromal cells (GC-MSCs) and GC-MSC-primed macrophages notably improved the migratory and invasive abilities of SC cells (Li et al. 2019). The gene discussed is CXCL8; the disease is gastric cancer.