Metabolism serves a key role in melanoma therapy escape as well as metastasis (8, 9), and we have shown that melanoma cells take up lipids through age-related expression of the SLC27A2 solute carrier family 27 member 2 also known as fatty acid transporter FATP2 in response to ceramides produced by aged fibroblasts, which are then utilized to escape therapy (5). This evidence concerns the gene SLC27A2 and melanoma.