Remarkably, by reviewing the most relevant gene sets of 3PO-induced genes on CRC in the protein atlas (NDUFB6, NDUFAB1, NDUFA4, CDC7, CDKN3, PLK4; ref. 64), we found that the increased expression of these proteins correlated with a better prognosis (Supplementary Fig. S6). Here, PLK4 is linked to colorectal carcinoma.