CCR2 and cancer: FC analysis performed on HIC derived from MC-38 injected mice revealed in OVX mice an increase in CXCR3 levels, on CD68+ hepatic macrophages (Fig. 3A) and in particular, in the CD11b+CCR2+CD68+ recruited monocyte/macrophage subset (Fig. 3B), suggesting that this receptor may play a role in monocyte/macrophage recruitment to the liver in response to metastatic cancer cells.