Among them, the distributions of memory B cells, resting CD4 memory T cells, CD4 memory activated T cells, and M1 macrophages were higher, while CD8 T cells, follicular helper T cells, Tregs, activated NK cells, monocytes and M0 macrophages were lower in the “hot” tumor (P < 0.05) (Figure 4B). Here, CD4 is linked to neoplasm.