Figures 8A, B showed the representative mIHC images of DAPI and three CMGs biomarkers in tumor tissues of responders and no-responders, i.e., DAPI (blue), CD86 (green), TNFRSF17 (purple) and TNFRSF1B (red). Further statistical analysis demonstrated that there were significant associations between high expression of CMGs biomarkers and patients’ positive response to immunotherapy (Figure 8C). This evidence concerns the gene CD86 and neoplasm.