Recently, a cohort research reported that DNMT3A‐CHIP is significantly linked to worse initial stroke severity as measured by the NIHSS score and is independently associated with a higher risk of hemorrhagic transformation (OR = 3.31, 95% CI = 1.81−6.07) and functional disability at 90 days post‐stroke (OR = 2.31, 95% CI = 1.17−4.53).7 This evidence concerns the gene DNMT3A and stroke disorder.