The clinical course of COVID-19 can quickly deteriorate to fatal consequences and ranges in severity from asymptomatic to a serious systemic illness with multiorgan and/or respiratory involvement [17-21]. White blood cell counts and MPV are utilized as indicators of the inflammatory response as a reflection of prothrombotic and pro-inflammatory factors such as a variety of cytokines of inflammation, including IL-1, IL-6, and TNF, which influences thermophoresis [21,22]. Here, TNF is linked to COVID-19.