GPT and Abnormal renal physiology: The patient had significant hepatic and renal dysfunction on admission (AST: 2,643 U/L, ALT: 1,219 U/L, LDH: 2,981 U/L, total bilirubin: 1.99 mg/dL, serum creatinine: 2.22 mg/dL), which may have prolonged the effect of edoxaban.