The 149 PCD-related DEGs significantly annotated by the necroptosis, ferroptosis and immunomodulatory pathways (lysosome, tuberculosis, IL–17 signaling pathway, rheumatoid arthritis, cytokine–cytokine receptor interaction, Influenza A) were selected by performing the KEGG pathway annotation analysis (Fig. 1C). Here, IL17A is linked to rheumatoid arthritis.