Network analysis has pinpointed drug-like compounds, including 2-linoleolglycerol, tremulone, spiro [2.5] non-4-ene, 4-ethyl-8-methylene-5-trimethylsilyl, ethyl (9Z, 12Z, 15Z)-octadeca-9,12,15-trienoate, stigmasteryl methyl ether and tricylo [20.8.0.0 (7,16)] triacontane, 1(22),7(16)-diepoxy targeting key proteins involved in cancer progressions and tumorigenesis, such as AKT1, MDM STAT3, EGFR, CDK2, MTOR, MAPK3 PTGS2, MCL1 and TNF among others. The gene discussed is PTGS2; the disease is cancer.