Interestingly, the interaction of HSPA2 with BAG6 (BCL2-associated athanogene 6; formerly BAT3, HLA-B-associated transcript 3) has been demonstrated to regulate its stability thereby making BAG6 a molecular target for idiopathic male infertility (Sasaki et al., 2008; Bromfield et al., 2015). This evidence concerns the gene BAG6 and male infertility.