We identified a total of 11 obesity associated genes showing enriched expression in hypothalamic neurons, including ACHE, ERBB4, GRID1, KCNK3, KCNK9, KSR2, NRXN3, NTRK2, PLXNA4, POMC and STX1B (Fig. 4E). This evidence concerns the gene KSR2 and obesity disorder.