B3galt5 has been associated with cancer-related proteins’ glycosylation due to its ability to catalyzes the galactosylation of glycosphingolipid globoside-4 (Gb4) to form globoside-5 (Gb5), which also known as SSEA3, a common cancer-specific marker highly expressed in breast cancer stem cells51. This evidence concerns the gene GNB5 and breast carcinoma.