Stratified by gene, path_MMR carriers had significantly different CRC curves from non-carriers at p<0.01 (log rank tests: path_MLH1: χ2=882.63, df=1, p=5.86×10−194; path_MSH2: χ2=236.81, df=1, p=1.92×10−53; path_MSH6: χ2=182.88, df=1, p=1.14×10−41; path_PMS2: χ2=7.05, df=1, p=0.008). This evidence concerns the gene MSH6 and colorectal carcinoma.