path_MMR carrier Nelson-Aalen curves for BC were not significantly different to the curve for non-carriers (Wilcoxon tests: path_MMR: W=1.22, p=0.27; path_MLH1: W=0.21, p=0.31; path_MSH2: W=1.02, p=0.31; path_MSH6: W=0.12, p=0.73; path_PMS2: W=0.95, p=0.33) (figure 4). The gene discussed is PMS2; the disease is breast cancer.