In vitro, TLR8 agonist stimulation of lung cancer cells resulted in the activation of NF‐κB, increased expression of proinflammatory factors (IL‐6, IL‐8, GM‐CSF, IL‐1α, and IL‐12), and increased expression of antiapoptotic proteins Bcl‐2, VEGFR2, and chemokine receptors [48]. The gene discussed is BCL2; the disease is lung carcinoma.