Individuals with a heightened degree of FMR displayed a greater trend towards advanced age, the presence of atrial fibrillation, classification within NYHA cardiac function class III or IV, as well as a higher propensity for reduced mean arterial pressure and elevated NT-pro-BNP levels, when contrasted with those exhibiting none/mild FMR (P < 0.05). Here, NPPB is linked to atrial fibrillation.