LRPAP1 and neoplasm: A recent study conducted by Peng et al. [202] showed that the combination of DNAzyme) with an intelligent nanosystem assembled by a pure RAP core and a MOF shell could passively accumulate in tumor tissue, impose potent gene silencing efficacy, and inhibited tumor growth after intravenous administration in breast tumor-bearing mouse models, offering opportunities for combined TNBC gene therapy.