In addition, the PDUI value of NIT2 was also negatively correlated with NIT2 gene expression level in both adjacent non-tumor tissues (Rs = −0.371, P = 4.12 × 10−3), LUAD tumor tissues (Rs = −0.320, P = 5.60 × 10−13), and total tissues (Rs = -0.361, P = 3.82 × 10−18) (Fig. 2d–f). This evidence concerns the gene NIT2 and neoplasm.