Three robust associations for ASIP with BCC (I2 = 42.55%; OR: 1.4176 95% CI: 1.3357–1.5031), KRT5 with BCC (I2 = 14.71%; OR: 2.1723, 95%CI: 1.9279–2.4476) and ASIP with MM (I2 = 97.92%; OR: 1.5966, 95%CI: 1.5037–1.6953) were confirmed by meta-analysis. Here, KRT5 is linked to skin basal cell carcinoma.