Disease-gene association enrichment analysis (FDR p < 0.05) indicated associations of ASIP with melanoma, cell type cancer, disease of cellular proliferation and cancer; of KRT5 with basal cell carcinoma, cell type cancer, carcinoma and disease of cellular proliferation and of SHBG with disease of cellular proliferation (Supplementary Fig. 9 and Supplementary Table 4). This evidence concerns the gene SHBG and melanoma.