Proteins associated with increased risk of BCC were ASIP (OR: 1.4014, 95% CI: 1.2891 to 1.5235), BOLA1 (OR: 1.1053, CI: 1.0534 to 1.1596), CLMP (OR: 1.1120, CI: 1.0495 to 1.1783), CNTN2 (OR: 1.0639, CI: 1.0289 to 1.1001), CTSS (OR: 1.1441, CI: 1.0618 to 1.2328), IRF3 (OR: 1.1502, CI: 1.0864 to 1.2179), KRT5 (OR: 2.4990, CI: 2.0071 to 3.1114), SHBG (OR: 1.2042, CI: 1.1078 to 1.3089) and TNFSF8 (OR: 1.2199, CI: 1.1019 to 1.3505). This evidence concerns the gene CTSS and skin basal cell carcinoma.