With no fine-tuning of our mammary tissue (GTEx) model, we see RNAPath is able to predict known marker genes, for example, PLIN1 in adipocytes (r score = 0.29, P-value = 2.27 × 10−19) (Supplementary Fig. 23) or breast cancer related genes like AQP1 (r score = 0.32, P-value = 1.58 × 10−23). The gene discussed is AQP1; the disease is breast carcinoma.