The preceding four significant variables were forced into the multivariate linear regression model and subsequently, it was revealed that serum secretoneurin levels had independent correlations with GCS scores (beta, -0.267; t = -3.055; 95% CI, -1.553 to -0.330; VIF, 1.183; P = 0.003) and hematoma volume (beta, 0.315; t = 3.370; 95% CI, 0.085 to 0.330; VIF, 1.353; P = 0.001), but not with intraventricular hemorrhage (beta, 0.108; t = 1.219; 95% CI, -1.745 to -7.312; VIF, 1.219; P = 0.226) and blood glucose levels (beta, 0.136; t = 1.659; 95% CI, -0.082 to 0.918; VIF, 1.041; P = 0.100). This evidence concerns the gene SCG2 and hematoma.