PDCD1 and infantile convulsions and choreoathetosis: In recent years, Gem/Cis (gemcitabine/cisplatin) chemotherapy combined with anti-PD-L1/PD-1 therapy has been recommended as the first-line regimen for advanced iCCA (MOK T S K, WU Y L, KUDABA et al. 2019; UENO et al. 2019).