Gamma-enolase, or neuron-specific enolase (NSE) is an isomer of the intracytoplasmic lycolytic enzyme enolase, which is found in neuronal bodies, axons, as well as neuroendocrine cells, neuroendocrine tumors, and neuroectodermal cells [31, 32]. This evidence concerns the gene ENO2 and neuroendocrine neoplasm.