This elevation suggested systemic atherosclerosis linked to impaired glucose tolerance.S1–3 On the other hand, serum expression of TNFRSF1A, CXCL4, MIP‐1 γ, MMP‐3, VEGFR2, IGF‐1, HGFR, OPN, and OPG was significantly lower in db/db mice. Here, TNFRSF1A is linked to Impaired glucose tolerance.