Midostaurin’s adverse effects include pancytopenia, infection, mucositis or stomatitis, pneumonitis or pulmonary infiltrates, GI tract intolerance (diarrhea, nausea), hepatotoxicity (increased alanine aminotransferase and hyperbilirubinemia), and electrolyte disturbances (hypokalemia, hyponatremia, hypophosphatemia, and hypocalcemia) [23]. This evidence concerns the gene GPT and Hyponatremia.