Two studies reported the use of prostate-specific antigen (PSA) and gamma-glutamyltransferase 1 (GGT1) to distinguish between normal or benign prostatic hyperplasia and prostate cancer patients, as the PSA and GGT1 protein levels were markedly higher in exosomes isolated from the blood of prostate cancer patients [38,39]. The gene discussed is KLK3; the disease is benign prostatic hyperplasia.