Particularly high rates of STING positivity occurred in SQCCs of different sites of origin (up to 96%), malignant mesothelioma (88.5–95.7%), ductal adenocarcinoma of the pancreas (94.9%), pulmonary adenocarcinoma (90.3%), cervical adenocarcinoma (90.0%), serous high-grade ovarian cancer (86.0%), anaplastic thyroid carcinoma (82.9%) colorectal adenocarcinoma (75.2%), adenocarcinoma of the gallbladder (68.8%), and in breast carcinoma (up to 66%). The gene discussed is STING1; the disease is malignant mesothelioma.