The presence of Piezo2-positive fibroblasts in the connective tissue surrounding some benign glands close to the carcinoma may be related to a neoplastic induction of a desmoplastic reaction and the delay of the healing process by non-tumor fibroblasts, as long as both Piezo channels are described to delay fibroblastic healing/scar processes [61]. The gene discussed is PIEZO2; the disease is carcinoma.