In this regard, we aim to evaluate and compare the genotype of these SNPs of KEAP1 (rs1048290) and of NRF2 (rs35652124, rs6721961, rs6706649) in blood, surrounding tissue and tumour tissue, and correlate it with clinicopathological data to evaluate a possible relation with breast cancer prognosis. This evidence concerns the gene KEAP1 and neoplasm.