Another level of control on ALDH1A3 expression in gliomas and other cancers comes from miRNA targeting ALDH1A3 transcripts: miR-187 and miR-1301-3p downregulate ALDH1A3 expression in prostate cancer [84,85], miR-200-ZEB1/SANI2 inhibits ALDH1A3 expression in colorectal cancer cells [86], miR-548 downregulates ALDH1A3 expression in hepatocellular carcinoma and macrophages [32], and miR320b and miR-4524b-5p do the same in human high-grade gliomas and GBM, resulting in decreased proliferation and increased resistance of glioma cells to irradiation [44,87]. Here, ZEB1 is linked to central nervous system cancer.