Furthermore, Blaye et al. identified eight genes on TILs in tumor-associated microenvironment in patients with TNBC and residual disease after NAC that were associated with metastatic relapse (BLK, GZMM, CXCR6, LILRA1, SPIB, CCL4, CXCR4, SLAMF7) in agreement with our findings showing CXCR4TIL expression was related with poor response to NAC [56]. The gene discussed is SPIB; the disease is neoplasm.