Notably, TP53 carriers were diagnosed with breast cancer earlier when compared to BRCA1 (24.75 y [3.00] vs. 27.96 y [2.41], p << 0.01) or BRCA2 carriers (24.75 y [3.00] vs. 28.36 [1.77], p << 0.01). This evidence concerns the gene TP53 and breast carcinoma.